Selecting an efficient structural system during the conceptual design of the new highway bridges is an essential requirement for the project's success and for meeting stakeholders' expectations. A large set of objective and subjective requirements must be considered and evaluated during bridge conceptual design based on multiple technical criteria. In addition, it is critical to incorporate clients' needs and expectations throughout the conceptual design stage to achieve their satisfaction toward the final project delivery. Existing literature lacks a structured methodology to assist designers in the selection process of the bridge structural system. For this reason, an integrated approach is proposed in this research to facilitate a structured decision-making process for evaluating different bridge structural systems during the conceptual design stage. The overarching goal is to choose the most optimal design that best meets the client's needs and technical requirements. The proposed methodology starts by identifying client needs and finding their relative importance by employing an Analytic Hierarchy Process (AHP) questionnaire, followed by determining the technical requirements in bridge conceptual design. A Quality Function Deployment (QFD) model is then developed to evaluate bridge structural systems. The main advantage of integrating QFD and AHP is to reduce the inconsistency and uncertainty in the QFD inputs. The developed methodology is implemented in a real case study of a bridge project in the United Arab Emirates (UAE). The results of the case study show that the proposed methodology can provide improved results in bridge structural system selection compared to the conventional approach. The proposed methodology is expected to benefit consulting companies, governmental authorities, and developers. Moreover, the major benefit would be enhancing the incorporation of client needs in the conceptual design stage of highway bridges. The current research utilized the proposed methodology at